Clinical trials2007–2008
Statistical analysis plans for a global oncology program
Designed and developed statistical analysis plans for a vast clinical-trial program for the oncology department of a large pharmaceutical company in New Jersey, one of the top 10 internationally.
Clinical trialsDecision analysis
Laparoscopic vs. abdominal hysterectomy
A randomized clinical trial and prospective cohort study compared surgical outcomes. We developed expert guidelines on the effects of shared decision-making and conducted the statistical analysis with repeated measures, nonparametric statistics and stratified analysis. A decision-tree model compared three surgery types.
OncologyBayesian
Breast cancer: tamoxifen vs. chemotherapy
A stochastic decision-tree model evaluated the survival benefit of adding chemotherapy to tamoxifen. We developed the Bayesian statistics for the model and ran the analysis of variance, correlation and nonparametric analyses.
Real-world evidenceMetabolic
EHR studies in diabetes and vitamin D deficiency
Managed large electronic-health-record datasets and applied multivariate and regression modeling to explore predictors of biochemical outcomes in type 2 diabetes, with sponsor-ready SAPs and outputs for international collaborations.
Real-world evidenceConsumer health
Evidence program for an OTC respiratory-health product
Led statistical strategy and data management for observational and pragmatic studies with quality-of-life and patient-reported endpoints, presenting findings to executive stakeholders to support product-lifecycle decisions.
Occupational healthU.S. DOE / NIOSH
Paducah gaseous diffusion plant workers study
A U.S. Department of Energy study funded by NIOSH of a fifty-year worker cohort, assessing cause-specific mortality and cancer incidence. Our role included preference analysis for roster development and quality assurance of data management in SAS.
Predictive analytics2009–2011
Forecasting asthma and allergy cases in schools
For a top-10 U.S. health insurer, we combined hourly measures of 10 air-pollution factors and twice-daily measures of 24 upper-air factors over three years to forecast asthmatic and allergic cases in Pennsylvania public schools.
Data miningPublished
BMI patterns among Pennsylvania schoolchildren
Data mining of large school-health datasets (Pre-K to Grade 12) revealed body-mass-index patterns; follow-on work modeled transitions between BMI categories using simulation. Findings appeared in the Journal of School Health and the American Journal of Public Health.
SimulationPublished
Healthcare reform: public concern and projected repercussions
Sentiment analysis and web-content analysis of online news and social media, plus stochastic-tree simulation of QALY outcomes under funding and coverage scenarios for people with multiple chronic conditions.
Market basket analysisPublished
Multiple and substitute addictions among adolescents
A retail data-mining technique, market basket analysis, was applied to reveal gateway and substitution patterns in prescription-drug misuse among twelfth graders (Journal of Addiction Medicine).
School healthMulti-year
School-health portal analytics for a health-services partner
Collaborated for three years with health-care organizations and the state of Pennsylvania on research using de-identified K-12 data from a coordinated school-health portal serving about 1,100 school buildings.
Development1995–1996
Old Cairo Tanneries relocation
Feasibility study, statistics and business plans for relocating the tanneries district from Old Cairo to Badr City, for Egypt’s Ministry of International Cooperation, with funding from Japan.
DevelopmentIndustrial sector
Assessing Egyptian industries’ needs to enter international markets
Investigation of development constraints to identify priorities and strategies for strengthening clients’ capabilities to compete globally, including MIS development and statistical analysis.
700factories
5industrial fields
Market research
Market study for a household-appliance manufacturer
Survey-based study of existing and potential customers and dealers to understand demographics, purchasing patterns, decision factors, brand awareness and competition for Zanussi Co. of Egypt.
Policy researchFord Foundation
Small-enterprise informality and regulatory reform
Economic and statistical analysis of how regulation affects small enterprises in leather, garment, metal and wood sectors.
$150Kfunding
450small businesses
DevelopmentUS-AID
Business incubators & training block grants
Feasibility study and business plans for two pilot business incubators on the Suez Canal ($3.5M), and design and operation of a management information system to monitor the US-AID Training Block Grants activity across Egypt ($5M).